Fecal microbiota transplantation alleviates cognitive impairment by improving gut microbiome composition and barrier function in male rats of traumatic brain injury following gas explosion

Fecal microbiota transplantation alleviates cognitive impairment by improving gut microbiome composition and barrier function in male rats of traumatic brain injury following gas explosion

BackgroundDysbiosis of gut microbiota (GM) is intricately linked with cognitive impairment and the incidence of traumatic brain injury (TBI) in both animal models and human subjects. However, there is limited understanding of the impact and mechanisms of fecal microbiota transplantation (FMT) on bra...

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Bibliographic Details
Main Authors: Xinwen Dong, Yaguang Su, Zheng Luo, Cuiying Li, Jie Gao, Xiaofeng Han, Sanqiao Yao, Weidong Wu, Linqiang Tian, Yichun Bai, Guizhi Wang, Wenjie Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Microbiology
Subjects:
gas explosion
cognitive impairment
microbiota-gut-brain axis
fecal microbiota transplantation
gut barrier function
16S rRNA gene sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1485936/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2024.1485936/full

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