Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis.

Mycobacterium tuberculosis synthesizes intra- and extracellular α-glucans that were believed to originate from separate pathways. The extracellular glucose polymer is the main constituent of the mycobacterial capsule that is thought to be involved in immune evasion and virulence. However, the role o...

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Bibliographic Details
Main Authors: Hendrik Koliwer-Brandl, Karl Syson, Robert van de Weerd, Govind Chandra, Ben Appelmelk, Marina Alber, Thomas R Ioerger, William R Jacobs, Jeroen Geurtsen, Stephen Bornemann, Rainer Kalscheuer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005768&type=printable
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