Reliability of CMV-IgG kinetics in the diagnosis of CMV primary infection: sensitivity, specificity, and clinical implications

Reliability of CMV-IgG kinetics in the diagnosis of CMV primary infection: sensitivity, specificity, and clinical implications

ABSTRACT Diagnosis of cytomegalovirus (CMV) primary infection (PI) during pregnancy relies on serology (CMV-IgG, IgM, and IgG avidity). However, as for toxoplasmosis, subsequent serology testing 3–5 weeks later is often performed to confirm the diagnosis. In this study, we aimed to show that testing...

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Main Authors: Vincent Portet Sulla, Rana Rafek, Isabelle Bertin-Jung, Jean-Pascal Siest, Elise Bouthry, Olivier Rogier, Abir Jadoui, Christelle Vauloup-Fellous, Claire Perillaud-Dubois
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
CMV
serology
IgM
avidity
pregnancy
IgG
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00455-25
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https://journals.asm.org/doi/10.1128/spectrum.00455-25

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