Associations of plasma SMOC1 and soluble IL6RA levels with the progression from mild cognitive impairment to dementia

Associations of plasma SMOC1 and soluble IL6RA levels with the progression from mild cognitive impairment to dementia

Despite the central role attributed to neuroinflammation in the etiology and pathobiology of Alzheimer's disease (AD), the direct link between levels of inflammatory mediators in blood and cerebrospinal fluid (CSF) compartments, as well as their potential implications for AD diagnosis and progr...

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Main Authors: Xavier Morató, Raquel Puerta, Amanda Cano, Adelina Orellana, Itziar de Rojas, María Capdevila, Laura Montrreal, Maitée Rosende-Roca, Pablo García-González, Claudia Olivé, Fernando García-Gutiérrez, Josep Blázquez, Andrea Miguel, Raúl Núñez-Llaves, Vanesa Pytel, Montserrat Alegret, María Victoria Fernández, Marta Marquié, Sergi Valero, Jose Enrique Cavazos, Santos Mañes, Mercè Boada, Alfredo Cabrera-Socorro, Agustín Ruiz
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
sIL6RA
SMOC1
Alzheimer's disease
Inflammation
Mild cognitive impairment
Disease progression
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354624001777
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