The bidirectional regulatory effect of TXNRD2 methylation in patients with chronic heart failure and its nonlinear dose-response relationship with key clinical parameters
Abstract Objective The research focused on examining CpG methylation within the TXNRD2 promoter area in chronic heart failure (CHF) patients, aiming to correlate methylation levels with clinical indexes to guide CHF treatment. Methods Whole blood samples from 20 CHF patients and 20 healthy controls...
Saved in:
| Main Authors: | Ruonan Zhao, Lin Ma, Ruiping Wang, Rongqiang Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
|
| Series: | Journal of Cardiothoracic Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13019-025-03495-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The methylation of TXNRD2 with chronic heart failure: the interaction effect between methylation regulation and clinical parameters-- a single center pilot study
by: Rongrong Chen, et al.
Published: (2025-08-01) -
Evaluating the amoeba thioredoxin reductase selenoprotein as potential drug target for treatment of Acanthamoeba infections
by: Alvie Loufouma-Mbouaka, et al.
Published: (2024-12-01) -
The inhibition of TXNRD1 by methylglyoxal impairs the intracellular control of Mycobacterium tuberculosis
by: Hanxiong Li, et al.
Published: (2025-09-01) -
Distinct roles for the thioredoxin and glutathione antioxidant systems in Nrf2-Mediated lung tumor initiation and progression
by: Amanda M. Sherwood, et al.
Published: (2025-06-01) -
Case report and literature review: novel TXNRD2 compound heterozygous variants in familial glucocorticoid deficiency type 5
by: Xiaoyan Wang, et al.
Published: (2025-07-01)