The bidirectional regulatory effect of TXNRD2 methylation in patients with chronic heart failure and its nonlinear dose-response relationship with key clinical parameters

Abstract Objective The research focused on examining CpG methylation within the TXNRD2 promoter area in chronic heart failure (CHF) patients, aiming to correlate methylation levels with clinical indexes to guide CHF treatment. Methods Whole blood samples from 20 CHF patients and 20 healthy controls...

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Bibliographic Details
Main Authors: Ruonan Zhao, Lin Ma, Ruiping Wang, Rongqiang Zhang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Online Access:https://doi.org/10.1186/s13019-025-03495-7
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