Ginkgo biloba extract alleviates oxygen and glucose deprivation/reperfusion injury in cardiac microvascular endothelial cells by regulating NF-κB and CHOP signaling pathways through SIRT6

Ginkgo biloba extract alleviates oxygen and glucose deprivation/reperfusion injury in cardiac microvascular endothelial cells by regulating NF-κB and CHOP signaling pathways through SIRT6

ObjectiveTo explore the effects of Ginkgo biloba extract (GBE) on cardiac microvascular endothelial cells (CMECs) under oxygen and glucose deprivation/reperfusion (OGD/R) condition and its molecular mechanisms. MethodsAn OGD/R-induced injury model was established in CMECs. According to different int...

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Bibliographic Details
Main Authors: Mukaddas ABDURAHMAN, Zhenyang GUO, Junbo GE, Hua LI
Format: Article
Language:English
Published: Shanghai Chinese Clinical Medicine Press Co., Ltd. 2025-02-01
Series:Zhongguo Linchuang Yixue
Subjects:
ginkgo biloba extract
cardiac microvascular endothelial cells
oxygen and glucose deprivation/reperfusion
endoplasmic reticulum stress
sirt6
Online Access:https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20241262
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https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20241262

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