Ifitm3 limits the severity of acute influenza in mice.

Interferon-induced transmembrane (IFITM) proteins are a family of viral restriction factors that inhibit the entry processes of several pathogenic viruses, including influenza A virus (IAV), in vitro. Here we report that IAV-infected knockout mice lacking the Ifitm locus on chromosome 7 exhibited ac...

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Bibliographic Details
Main Authors: Charles C Bailey, I-Chueh Huang, Christina Kam, Michael Farzan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002909&type=printable
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