Heat shock factor 2 is a stress‐responsive mediator of neuronal migration defects in models of fetal alcohol syndrome

Heat shock factor 2 is a stress‐responsive mediator of neuronal migration defects in models of fetal alcohol syndrome

Abstract Fetal alcohol spectrum disorder (FASD) is a frequent cause of mental retardation. However, the molecular mechanisms underlying brain development defects induced by maternal alcohol consumption during pregnancy are unclear. We used normal and Hsf2‐deficient mice and cell systems to uncover a...

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Main Authors: Rachid El Fatimy, Federico Miozzo, Anne Le Mouël, Ryma Abane, Leslie Schwendimann, Délara Sabéran‐Djoneidi, Aurélie de Thonel, Illiasse Massaoudi, Liliana Paslaru, Kazue Hashimoto‐Torii, Elisabeth Christians, Pasko Rakic, Pierre Gressens, Valérie Mezger
Format: Article
Language:English
Published: Springer Nature 2014-07-01
Series:EMBO Molecular Medicine
Subjects:
fetal alcohol syndrome
heat shock factors
microtubule‐associated proteins
radial neuronal migration
transcription
Online Access:https://doi.org/10.15252/emmm.201303311
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https://doi.org/10.15252/emmm.201303311

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