Efficacy of D,L-methadone in the treatment of glioblastoma in vitro

Efficacy of D,L-methadone in the treatment of glioblastoma in vitro

Aim: Recently, D,L-methadone has been put forward as adjuvant treatment in glioblastoma (GBM). Methods: We analyzed the μ-opioid receptor expression in a set of GBM cell lines and investigated the efficacy of D,L-methadone alone and in combination with temozolomide (TMZ). Results & conclusion: E...

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Main Authors: Konstantin Brawanski, Gero Brockhoff, Peter Hau, Arabel Vollmann-Zwerenz, Christian Freyschlag, Annette Lohmeier, Markus J Riemenschneider, Claudius Thomé, Alexander Brawanski, Martin A Proescholdt
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:CNS Oncology
Subjects:
adjuvant treatment
glioblastoma
methadone
temozolomide
Online Access:https://www.futuremedicine.com/doi/10.2217/cns-2018-0006
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https://www.futuremedicine.com/doi/10.2217/cns-2018-0006

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