Comparative study of adipose tissue derived mesenchymal stem cells with rapamycin on paraquat-induced acute lung injury and pulmonary fibrosis in a mouse model: histological and biochemical study

Comparative study of adipose tissue derived mesenchymal stem cells with rapamycin on paraquat-induced acute lung injury and pulmonary fibrosis in a mouse model: histological and biochemical study

Abstract Background The most noticeable consequence of paraquat (PQ) toxicity is pulmonary fibrosis. Mesenchymal stem cells have the remarkable ability to self-renew and differentiate into many cell types. One such type is adipose tissue-derived Mesenchymal Stem Cells (AT-MSCs), which are derived fr...

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Bibliographic Details
Main Authors: Heba Fikry, Lobna A. Saleh, Doaa R. Sadek
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Adipose tissue
Lung injury
Pulmonary fibrosis
Rapamycin
Paraquat
Online Access:https://doi.org/10.1186/s13287-025-04498-w
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https://doi.org/10.1186/s13287-025-04498-w

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