The Impact of HIV on B Cell Compartment and Its Implications for COVID-19 Vaccinations in People with HIV

The Impact of HIV on B Cell Compartment and Its Implications for COVID-19 Vaccinations in People with HIV

HIV causes intense polyclonal activation of B cells, resulting in increased numbers of spontaneously antibody-secreting cells in the circulation and hypergammaglobulinemia. It is accompanied by significant perturbations in various B cell subsets, such as increased frequencies of immature/transitiona...

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Bibliographic Details
Main Authors: Lixing Wang, Branka Vulesevic, MariaLuisa Vigano, Alia As’sadiq, Kristina Kang, Cristina Fernandez, Suzanne Samarani, Aslam H. Anis, Ali Ahmad, Cecilia T. Costiniuk
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Vaccines
Subjects:
anti-SARS-CoV-2 vaccines
ART
B cells
COVID-19
HIV
PWH
Online Access:https://www.mdpi.com/2076-393X/12/12/1372
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