PCR-detection rates of T. pallidum ssp. pallidum in swab samples from the Czech Republic (2004–2022): Combined RPR, IgM, and PCR tests efficiently detect active syphilis

PCR-detection rates of T. pallidum ssp. pallidum in swab samples from the Czech Republic (2004–2022): Combined RPR, IgM, and PCR tests efficiently detect active syphilis

Syphilis is a multistage sexually transmitted disease caused by Treponema pallidum ssp. pallidum (TPA). This study analyzed clinical samples collected from patients with a diagnosed syphilis infection from 2004–2022, isolated in the Czech Republic. Mucocutaneous swab samples (n = 543) from 543 patie...

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Main Authors: Eliška Vrbová, Petra Pospíšilová, Eliška Dastychová, Martina Kojanová, Miluše Kreidlová, Daniela Vaňousová, Filip Rob, Přemysl Procházka, Alena Krchňáková, Vladimír Vašků, Radim Strnadel, Olga Faustmannová, Monika Dvořáková Heroldová, Ivana Kuklová, Hana Zákoucká, David Šmajs
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:International Journal of Medical Microbiology
Subjects:
Syphilis
Syphilis diagnostics
PCR syphilis detection
RPR
Syphilis serology
Nontreponemal tests
Online Access:http://www.sciencedirect.com/science/article/pii/S1438422125000037
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