Huperzine A Alleviates Mechanical Allodynia but Not Spontaneous Pain via Muscarinic Acetylcholine Receptors in Mice

Chronic pain is a major health issue and most patients suffer from spontaneous pain. Previous studies suggest that Huperzine A (Hup A), an alkaloid isolated from the Chinese herb Huperzia serrata, is a potent analgesic with few side effects. However, whether it alleviates spontaneous pain is uncl...

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Bibliographic Details
Main Authors: Zhen-Xing Zuo, Yong-Jie Wang, Li Liu, Yiner Wang, Shu-Hao Mei, Zhi-Hui Feng, Maode Wang, Xiang-Yao Li
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2015/453170
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