Ferroptosis in ocular diseases: mechanisms, crosstalk with other cell death pathways, and therapeutic prospects
BackgroundOcular diseases pose a significant threat to visual health, with ferritin ferroptosis playing a critical role in the pathogenesis of many such conditions. Ferritin accumulation, coupled with ferritin autophagy-mediated release of labile Fe2+, triggers iron-dependent lipid peroxidation and...
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| Main Authors: | Shuai Huang, Yuying Sun, Xinxin Yu, Xuan Ren, Lei Wang, Yan Sun, Aijun Deng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1608975/full |
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