Ferroptosis in ocular diseases: mechanisms, crosstalk with other cell death pathways, and therapeutic prospects

BackgroundOcular diseases pose a significant threat to visual health, with ferritin ferroptosis playing a critical role in the pathogenesis of many such conditions. Ferritin accumulation, coupled with ferritin autophagy-mediated release of labile Fe2+, triggers iron-dependent lipid peroxidation and...

Full description

Saved in:
Bibliographic Details
Main Authors: Shuai Huang, Yuying Sun, Xinxin Yu, Xuan Ren, Lei Wang, Yan Sun, Aijun Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1608975/full
Tags: Add Tag
No Tags, Be the first to tag this record!