Quality and composition control of complex TCM preparations through a novel “Herbs-in vivo Compounds-Targets-Pathways” network methodology: The case of Lianhuaqingwen capsules

Quality and composition control of complex TCM preparations through a novel “Herbs-in vivo Compounds-Targets-Pathways” network methodology: The case of Lianhuaqingwen capsules

Lianhuaqingwen (LHQW) capsules, a Chinese patent medicine composed of 13 herbal ingredients, are widely used for respiratory diseases. However, the complex composition of LHQW poses challenges in assessing its quality and consistency. In this study, a comprehensive network of LHQW was constructed by...

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Main Authors: Simian Chen, Hui Qi, Chunyan Zhu, Yiheng Zhao, Bo Jiao, Yun Tan, Yuexin Yang, Tongxing Wang, Yunlong Hou, Binxin Dai, Dandan Zhang, Hairong Zhang, Junyu Zhang, Xiaojuan Jiang, Xiaodan Guo, Xiaoyu Qian, Caixia Yuan, Xue Bai, Jiayun Chen, Suping Wang, Yu Cai, Jiarou Zhong, Yunqi Li, Qianqian Zhang, Zhenhua Jia, Caisheng Wu
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Pharmacological Research
Subjects:
Lianhuaqingwen
Quality control markers
Digital RNA with pertUrbation of Genes
RNA-seq
Pharmacokinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825000751
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