An Assessment of Surface Contamination and Dermal Exposure to 5-Fluorouracil in Healthcare Settings by UPLC-MS/MS Using a New Atmospheric Pressure Ionization Source

An Assessment of Surface Contamination and Dermal Exposure to 5-Fluorouracil in Healthcare Settings by UPLC-MS/MS Using a New Atmospheric Pressure Ionization Source

5-Fluorouracil (5-FU) is a well-known cytostatic drug, which is often used in cancer treatments. Yet, it is also a very dangerous compound for people who are occupationally exposed to it for a long time, such as pharmacy employees, nurses and cleaning staff. We aimed to improve and implement a LC-MS...

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Bibliographic Details
Main Authors: Matteo Creta, Eline Verscheure, Birgit Tans, Herman Devriese, An Devriendt, David Devolder, Robin Lebegge, Katrien Poels, Lode Godderis, Radu-Corneliu Duca, Jeroen A. J. Vanoirbeek
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Toxics
Subjects:
5-fluorouracil
antineoplastic drug
occupational exposure
Online Access:https://www.mdpi.com/2305-6304/12/11/766
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