Tat-specific antibodies associated with better HIV-associated motor function

Tat-specific antibodies associated with better HIV-associated motor function

Abstract Tat is a transactivator of HIV transcription that can be secreted to affect nearby cells. Deleterious central nervous system effects of extracellular Tat include dopaminergic neuron dysfunction, raising the possibility that Tat secretion may be linked to Parkinsonian motor features seen in...

Full description

Saved in:
Bibliographic Details
Main Authors: Catarina E. Hioe, Clauvis Kunkeng Yengo, Xiaomei Liu, Reuben Davis, Gospel Enyindah-Asonye, Jéromine Klingler, Alex F. Tang, Juan C. Bandres, Anuradha Ganesan, Tahaniyat Lalani, Joseph Yabes, Brian K. Agan, Xiaokun Liu, David J. Volsky, Susan Morgello, Jessica Robinson-Papp
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
HIV
Tat
Antibodies
Epitopes
Dopaminergic neuron
Neuropathogenesis
Online Access:https://doi.org/10.1038/s41598-025-12624-0
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-12624-0

Similar Items