Protection from malaria infection using liver-targeted siRNA

Malaria-causing Plasmodium parasites infect the liver and undergo obligate and asymptomatic replication in hepatocytes prior to infection of the blood. As such, preventing liver infection will prevent blood infection, thereby prevent malaria disease, and the spread of parasites by mosquitoes. The te...

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Bibliographic Details
Main Authors: R.W.J. Steel, A. Schepis, T. Nguyen, S. Milstein, K. Yucius, H.C. Tu, E. Fishilevich, P. Haslett, S.H.I. Kappe
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Molecular Therapy: Methods & Clinical Development
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Online Access:http://www.sciencedirect.com/science/article/pii/S2329050125001111
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