PROTACs improve selectivity for targeted proteins

Proteolysis targeting chimera (PROTAC) technology has emerged as a powerful tool in drug discovery that enables targeted protein degradation through a unique bifunctional approach. This review provides a comprehensive overview of PROTACs with a focus on recent advances in enhancing selectivity and t...

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Bibliographic Details
Main Authors: Lihua Liu, Xian Guan, Jiezhen Zhuo, Xifeng Wu, Xin Han
Format: Article
Language:English
Published: Compuscript Ltd 2025-04-01
Series:Acta Materia Medica
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2025-0015
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