HyPepTox-Fuse: An interpretable hybrid framework for accurate peptide toxicity prediction fusing protein language model-based embeddings with conventional descriptors

Peptide-based therapeutics hold great promise for the treatment of various diseases; however, their clinical application is often hindered by toxicity challenges. The accurate prediction of peptide toxicity is crucial for designing safe peptide-based therapeutics. While traditional experimental appr...

Full description

Saved in:
Bibliographic Details
Main Authors: Duong Thanh Tran, Nhat Truong Pham, Nguyen Doan Hieu Nguyen, Leyi Wei, Balachandran Manavalan
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177925002278
Tags: Add Tag
No Tags, Be the first to tag this record!