Exosome circ-CBLB promotes M1 macrophage polarization in rheumatoid arthritis through the TLR3/TRAF3 signaling axis

BackgroundRheumatoid arthritis (RA) is a chronic autoimmune condition characterized by persistent inflammation of the joint’s synovial membrane. This inflammation leads to the degradation of joint cartilage and bone, resulting in joint dysfunction and deformity. Early symptoms of RA are often subtle...

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Bibliographic Details
Main Authors: Mengyu Zhang, Lei Wan, Xiaojun Zhang, Siyu Wang, Feng Li, Dawei Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1627389/full
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