Safety, pharmacokinetics, preliminary efficacy, pharmacodynamics, and immunogenicity of QX002N, an anti-IL-17A monoclonal antibody, after short-term treatment of active ankylosing spondylitis

Abstract Background To investigate the safety, pharmacokinetics, preliminary efficacy, pharmacodynamics, and immunogenicity of QX002N, an interleukin-17 A monoclonal antibody, in Chinese patients with active ankylosing spondylitis (AS). Methods In this phase 1b, double-blind, placebo-controlled, mul...

Full description

Saved in:
Bibliographic Details
Main Authors: Min Wu, Qianqian Li, Min Fang, Hong Zhang, Yanhua Ding
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s40360-025-00885-4
Tags: Add Tag
No Tags, Be the first to tag this record!