Integrin signaling in tumor biology: mechanisms of intercellular crosstalk and emerging targeted therapies
Integrins, a family of transmembrane cell adhesion receptors, mediate intercellular and cell–extracellular matrix crosstalk via outside-in and inside-out signaling pathways. Integrins, categorized into 24 distinct combinations of α and β subunits, exhibit tissue-specific expression and perform uniqu...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PeerJ Inc.
2025-05-01
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| Series: | PeerJ |
| Subjects: | |
| Online Access: | https://peerj.com/articles/19328.pdf |
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