In vitro Antitumor Activity and Electrochemical Studies of Bio-Electroactive Anthraquinone Derivatives in Glioblastoma

In vitro Antitumor Activity and Electrochemical Studies of Bio-Electroactive Anthraquinone Derivatives in Glioblastoma

Abstract This study investigated the antiglioblastoma potential of nine synthetic anthraquinone derivatives (SAQDs). SAQDs were tested for their in vitro cytotoxicity against PBMCs and GBM02 cells. For PBMC, SAQDs showed no cytotoxic effects up to 100 µM. Four most promising SAQDs (1, 4, 5, and 9) d...

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Main Authors: SUELLEN MARIA A. DA SILVA, JOÃO KAYCKE S. DA SILVA, JOICE FRAGOSO O. DE ARAÚJO, ANDRESSA LETÍCIA L. DA SILVA, ANDRESA KATHERINE A. DE ALMEIDA, TAMIRES A. DO NASCIMENTO, ANDRÉ FELIPPE A. XAVIER, RENATA G. DE ALMEIDA, GUILHERME AUGUSTI M. JARDIM, EUFRÂNIO N. DA SILVA JÚNIOR, VIVALDO MOURA-NETO, ALYSSON WAGNER F. DUARTE, PIERRE BARNABÉ ESCODRO, JOÃO XAVIER DE ARAÚJO JÚNIOR, MARÍLIA O.F. GOULART, ALINE C. DE QUEIROZ, MAGNA SUZANA ALEXANDRE-MOREIRA
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2025-06-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
anthraquinones
cells
glioblastoma
electroactivity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652025000300601&lng=en&tlng=en
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