Longitudinal Analyses and Predictive Factors of Radiation-Induced Lymphopenia After Postmastectomy Hypofractionated Radiation Therapy for Breast Cancer: A Pooled Cohort Study of 2 Prospective Trials

Purpose: Radiation-induced lymphopenia (RIL) correlates with poor prognoses in solid tumors. This study aimed to investigate the post–radiation therapy (RT) longitudinal lymphocyte changes and the impact of different RT techniques on RIL in breast cancer patients. Methods and Materials: We prospecti...

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Main Authors: Xu-Ran Zhao, MD, Hui Fang, MD, Hao Jing, MD, Qiu-Zi Zhong, MD, Hong-Fen Wu, MD, Xiao-Rong Hou, MD, Li-Hua Dong, MD, Ya-Hua Zhong, MD, Jing Jin, MD, Li-Na Zhao, MD, Xiao-Hong Wang, MD, Wei-Fang Yang, MD, Jian Tie, MD, Yu-Fei Lu, MD, Guang-Yi Sun, MD, Dan-Qiong Wang, MD, Yu Tang, MD, Shu-Nan Qi, MD, Yong-Wen Song, MD, Yue-Ping Liu, MD, Yuan Tang, MD, Ning-Ning Lu, MD, Bo Chen, MD, Wen-Wen Zhang, MD, Yi-Rui Zhai, MD, Shang-Ying Hu, Jun Zhang, MD, Ye-Xiong Li, MD, Na Zhang, MD, Shu-Lian Wang, MD
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109425000387
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