Sex-specific attenuation of photoreceptor degeneration by reserpine in a rhodopsin P23H rat model of autosomal dominant retinitis pigmentosa

Sex-specific attenuation of photoreceptor degeneration by reserpine in a rhodopsin P23H rat model of autosomal dominant retinitis pigmentosa

Inherited retinal degenerations (IRDs) constitute a group of clinically and genetically diverse vision-impairing disorders. Retinitis pigmentosa (RP), the most common form of IRD, is characterized by gradual dysfunction and degeneration of rod photoreceptors, followed by the loss of cone photorecept...

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Bibliographic Details
Main Authors: Hyun Beom Song, Laura Campello, Anupam Mondal, Holly Y Chen, Milton A English, Michael Glen, Phillip Vanlandingham, Rafal Farjo, Anand Swaroop
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-04-01
Series:eLife
Subjects:
small molecule drug
retinal degeneration
neuroprotection
rhodopsin mutation
retinitis pigmentosa
Online Access:https://elifesciences.org/articles/103888
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https://elifesciences.org/articles/103888

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