Sensitization to food allergies in the context of atopic comorbidity
The lecture considers a place of food allergy in the profile of allergic and, in particular, atopic diseases and its features, distinguishing this pathology from all other allergies. Three classes of food allergens are characterized, and sensitization to them involving cells and regulatory molecules...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2025-07-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/6064 |
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| author | P. Yu. Isaev O. I. Urazova V. V. Klimov M. I. Musina D. S. Zagreshenko A. A. Denisov Ya. V. Kukharev A. N. Shkatova A. V. Klimov |
| author_facet | P. Yu. Isaev O. I. Urazova V. V. Klimov M. I. Musina D. S. Zagreshenko A. A. Denisov Ya. V. Kukharev A. N. Shkatova A. V. Klimov |
| author_sort | P. Yu. Isaev |
| collection | DOAJ |
| description | The lecture considers a place of food allergy in the profile of allergic and, in particular, atopic diseases and its features, distinguishing this pathology from all other allergies. Three classes of food allergens are characterized, and sensitization to them involving cells and regulatory molecules, such as neurotransmitters, neuropeptides, cytokines, and others mediators, is described in detail.At the current level of science, the mechanisms of oral tolerance and the causes of its breakdown are considered, resulting in clinical manifestations of food allergies, characterized by high polymorphism and complexity of diagnosis. Not only is a high rate of comorbidity of food allergies emphasized, but also its exceptional risks are pinpointed in terms of the development of anaphylactic shock, which is a difficult issue to explain in nutrition and digestion. The final part of the lecture is devoted to current and future therapeutic interventions in this pathology. |
| format | Article |
| id | doaj-art-cd651c9245264fdaa2cb16d925924ad0 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-cd651c9245264fdaa2cb16d925924ad02025-08-20T03:37:46ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842025-07-0124215316110.20538/1682-0363-2025-2-153-1613166Sensitization to food allergies in the context of atopic comorbidityP. Yu. Isaev0O. I. Urazova1V. V. Klimov2M. I. Musina3D. S. Zagreshenko4A. A. Denisov5Ya. V. Kukharev6A. N. Shkatova7A. V. Klimov8Kanevskaya Central HospitalSiberian State Medical UniversitySiberian State Medical UniversityStudent PolyclinicRussian Medical Academy for Continuing Postgraduate Education, Novokuznetsk branchSiberian State Medical UniversitySiberian State Medical UniversityStudent PolyclinicSiberian State Medical UniversityThe lecture considers a place of food allergy in the profile of allergic and, in particular, atopic diseases and its features, distinguishing this pathology from all other allergies. Three classes of food allergens are characterized, and sensitization to them involving cells and regulatory molecules, such as neurotransmitters, neuropeptides, cytokines, and others mediators, is described in detail.At the current level of science, the mechanisms of oral tolerance and the causes of its breakdown are considered, resulting in clinical manifestations of food allergies, characterized by high polymorphism and complexity of diagnosis. Not only is a high rate of comorbidity of food allergies emphasized, but also its exceptional risks are pinpointed in terms of the development of anaphylactic shock, which is a difficult issue to explain in nutrition and digestion. The final part of the lecture is devoted to current and future therapeutic interventions in this pathology.https://bulletin.ssmu.ru/jour/article/view/6064food allergenssensitizationcomorbidityanaphylaxisoral tolerance |
| spellingShingle | P. Yu. Isaev O. I. Urazova V. V. Klimov M. I. Musina D. S. Zagreshenko A. A. Denisov Ya. V. Kukharev A. N. Shkatova A. V. Klimov Sensitization to food allergies in the context of atopic comorbidity Бюллетень сибирской медицины food allergens sensitization comorbidity anaphylaxis oral tolerance |
| title | Sensitization to food allergies in the context of atopic comorbidity |
| title_full | Sensitization to food allergies in the context of atopic comorbidity |
| title_fullStr | Sensitization to food allergies in the context of atopic comorbidity |
| title_full_unstemmed | Sensitization to food allergies in the context of atopic comorbidity |
| title_short | Sensitization to food allergies in the context of atopic comorbidity |
| title_sort | sensitization to food allergies in the context of atopic comorbidity |
| topic | food allergens sensitization comorbidity anaphylaxis oral tolerance |
| url | https://bulletin.ssmu.ru/jour/article/view/6064 |
| work_keys_str_mv | AT pyuisaev sensitizationtofoodallergiesinthecontextofatopiccomorbidity AT oiurazova sensitizationtofoodallergiesinthecontextofatopiccomorbidity AT vvklimov sensitizationtofoodallergiesinthecontextofatopiccomorbidity AT mimusina sensitizationtofoodallergiesinthecontextofatopiccomorbidity AT dszagreshenko sensitizationtofoodallergiesinthecontextofatopiccomorbidity AT aadenisov sensitizationtofoodallergiesinthecontextofatopiccomorbidity AT yavkukharev sensitizationtofoodallergiesinthecontextofatopiccomorbidity AT anshkatova sensitizationtofoodallergiesinthecontextofatopiccomorbidity AT avklimov sensitizationtofoodallergiesinthecontextofatopiccomorbidity |