Harshly Oxidized Activated Charcoal Enhances Protein Persulfidation with Implications for Neurodegeneration as Exemplified by Friedreich’s Ataxia

Harshly Oxidized Activated Charcoal Enhances Protein Persulfidation with Implications for Neurodegeneration as Exemplified by Friedreich’s Ataxia

Harsh acid oxidation of activated charcoal transforms an insoluble carbon-rich source into water-soluble, disc structures of graphene decorated with multiple oxygen-containing functionalities. We term these pleiotropic nano-enzymes as “pleozymes”. A broad redox potential spans many crucial redox rea...

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Bibliographic Details
Main Authors: Anh T. T. Vo, Uffaf Khan, Anton V. Liopo, Karthik Mouli, Kenneth R. Olson, Emily A. McHugh, James M. Tour, Madhavan Pooparayil Manoj, Paul J. Derry, Thomas A. Kent
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Nanomaterials
Subjects:
nanozyme
persulfidation
Nrf2
Keap1
oxidized activated carbon nanoparticles
Online Access:https://www.mdpi.com/2079-4991/14/24/2007
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