Multitargeted biological actions of polydatin in preventing pseudogout acute attack

Multitargeted biological actions of polydatin in preventing pseudogout acute attack

IntroductionWe have recently shown that polydatin (PD) prevents calcium pyrophosphate (CPP) crystal-induced arthritis in mice. This study aims to explore potential mechanisms of action associated with this anti-inflammatory effect.Materials and methodsAcute arthritis was induced in Balb/c mice by th...

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Main Authors: Chiara Baggio, Paola Galozzi, Amelia Damasco, Vanni Lazzarin, Giampietro Ravagnan, Paolo Sfriso, Roberta Ramonda, Leonardo Punzi, Gianmaria Pennelli, Andrea Doria, Roberto Luisetto, Francesca Oliviero
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
polydatin
calcium pyrophosphate crystals
crystal-induced inflammation
inflammation
interleukin-1β
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1553912/full
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https://www.frontiersin.org/articles/10.3389/fmolb.2025.1553912/full

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