Simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm: A rare manifestation

Malignant acanthosis nigricans (MAN) is a paraneoplastic dermatosis associated most commonly with an underlying intra-abdominal malignancy. It may manifest either with or before the development of the malignancy prompt diagnosis of such paraneoplastic syndrome is often instrumental in early diagnosi...

Full description

Saved in:
Bibliographic Details
Main Authors: Jayati Dave, Sunanda Mahajan, Ankita Maheshwari, Abhishek Gupta
Format: Article
Language:English
Published: SAGE Publishing 2020-01-01
Series:Indian Journal of Rheumatology
Subjects:
Online Access:http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=4;spage=362;epage=365;aulast=Dave
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832544158150033408
author Jayati Dave
Sunanda Mahajan
Ankita Maheshwari
Abhishek Gupta
author_facet Jayati Dave
Sunanda Mahajan
Ankita Maheshwari
Abhishek Gupta
author_sort Jayati Dave
collection DOAJ
description Malignant acanthosis nigricans (MAN) is a paraneoplastic dermatosis associated most commonly with an underlying intra-abdominal malignancy. It may manifest either with or before the development of the malignancy prompt diagnosis of such paraneoplastic syndrome is often instrumental in early diagnosis of occult malignancy. Palmar fasciitis and polyarthritis syndrome is a rare disease characterized by palmar fasciitis, symmetric synovitis of the hands, fibrosis, and flexion contractures. We present a case of a 48-year-old female who presented with complaints of bilateral contracture of hands with diffuse hyperpigmentation over body folds, face, and trunk suggestive of MAN. On investigation, she was found to have ovarian carcinoma. The hand contracture was thought to be due to palmar fasciitis with polyarthritis syndrome. The patient underwent total abdominal hysterectomy with bilateral total salpingo-oophorectomy with subtle improvement in acanthosis nigricans.
format Article
id doaj-art-ccd1ca4c20eb485abab3a1881b7efcad
institution Kabale University
issn 0973-3698
0973-3701
language English
publishDate 2020-01-01
publisher SAGE Publishing
record_format Article
series Indian Journal of Rheumatology
spelling doaj-art-ccd1ca4c20eb485abab3a1881b7efcad2025-02-03T10:55:03ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012020-01-0115436236510.4103/injr.injr_99_20Simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm: A rare manifestationJayati DaveSunanda MahajanAnkita MaheshwariAbhishek GuptaMalignant acanthosis nigricans (MAN) is a paraneoplastic dermatosis associated most commonly with an underlying intra-abdominal malignancy. It may manifest either with or before the development of the malignancy prompt diagnosis of such paraneoplastic syndrome is often instrumental in early diagnosis of occult malignancy. Palmar fasciitis and polyarthritis syndrome is a rare disease characterized by palmar fasciitis, symmetric synovitis of the hands, fibrosis, and flexion contractures. We present a case of a 48-year-old female who presented with complaints of bilateral contracture of hands with diffuse hyperpigmentation over body folds, face, and trunk suggestive of MAN. On investigation, she was found to have ovarian carcinoma. The hand contracture was thought to be due to palmar fasciitis with polyarthritis syndrome. The patient underwent total abdominal hysterectomy with bilateral total salpingo-oophorectomy with subtle improvement in acanthosis nigricans.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=4;spage=362;epage=365;aulast=Davemalignant acanthosis nigricansovarian carcinomapalmar fasciitis with polyarthritis syndrome
spellingShingle Jayati Dave
Sunanda Mahajan
Ankita Maheshwari
Abhishek Gupta
Simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm: A rare manifestation
Indian Journal of Rheumatology
malignant acanthosis nigricans
ovarian carcinoma
palmar fasciitis with polyarthritis syndrome
title Simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm: A rare manifestation
title_full Simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm: A rare manifestation
title_fullStr Simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm: A rare manifestation
title_full_unstemmed Simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm: A rare manifestation
title_short Simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm: A rare manifestation
title_sort simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm a rare manifestation
topic malignant acanthosis nigricans
ovarian carcinoma
palmar fasciitis with polyarthritis syndrome
url http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=4;spage=362;epage=365;aulast=Dave
work_keys_str_mv AT jayatidave simultaneouspresentationofmalignantacanthosisnigricansandpalmarfasciitiswithpolyarthritissyndromeinapatientofovarianneoplasmararemanifestation
AT sunandamahajan simultaneouspresentationofmalignantacanthosisnigricansandpalmarfasciitiswithpolyarthritissyndromeinapatientofovarianneoplasmararemanifestation
AT ankitamaheshwari simultaneouspresentationofmalignantacanthosisnigricansandpalmarfasciitiswithpolyarthritissyndromeinapatientofovarianneoplasmararemanifestation
AT abhishekgupta simultaneouspresentationofmalignantacanthosisnigricansandpalmarfasciitiswithpolyarthritissyndromeinapatientofovarianneoplasmararemanifestation