Processing‐induced reduction in dianthrones content and toxicity of Polygonum multiflorum: Insights from ultra‐high performance liquid chromatography triple quadrupole mass spectrometry analysis and toxicological assessment

Abstract Background Polygonum multiflorum‐induced liver injury (PM‐DILI) has significantly hindered its clinical application and development. Methods This study investigates the variation in content and toxicity of dianthrones, the toxic components of P. multiflorum, during different processing cycl...

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Bibliographic Details
Main Authors: Wan‐Fang Li, Ying Wang, Cai‐Xia Qiu, Jie Li, Jie Bao, Jian‐Bo Yang, Hong‐Tao Jin
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Animal Models and Experimental Medicine
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Online Access:https://doi.org/10.1002/ame2.12474
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