Stereospecific α-glucosidase inhibition, kinetics, and molecular docking studies on isolated diastereomeric alkaloids from Uncaria longiflora

Stereospecific α-glucosidase inhibition, kinetics, and molecular docking studies on isolated diastereomeric alkaloids from Uncaria longiflora

The stem extract of Uncaria longiflora var. pteropoda (Rubiaceae) has been reported to possess strong α-glucosidase inhibition. However, the specific compounds contributing to this inhibitory potential have not yet been determined. The aim of the present work was to isolate phytochemicals from the m...

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Main Authors: Nurul Aina Suzlin Sulaiman, Muhammad Farhan Syakir Nor Azman, Mohd Fadhlizil Fasihi Mohd Aluwi, Zainul Amiruddin Zakaria, Mohammad Jemain Mohammad Ridhwana, Fatimah Salim
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Results in Chemistry
Subjects:
Uncaria
Alkaloid
Alpha-glucosidase
Molecular docking
Recycling HPLC
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624006222
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