AlkTango reveals a role for Jeb/Alk signaling in the Drosophila heart

Abstract Anaplastic lymphoma kinase (Alk) signaling is important in a variety of biological contexts such as cell type specification, regulation of metabolic and endocrine programs, behavior, and cancer. In this work, we generated a Tango GPCR assay-based, dimerization-sensitive Alk activity reporte...

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Bibliographic Details
Main Authors: G Wolfstetter, T Masudi, E Uçkun, J Y Zhu, M Yi, V Anthonydhason, J Guan, H Sonnenberg, Z Han, R H Palmer
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cell Communication and Signaling
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Online Access:https://doi.org/10.1186/s12964-025-02150-x
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