Precise Detection of Gene Mutations in Fine-Needle Aspiration Specimens of the Papillary Thyroid Microcarcinoma Using Next-Generation Sequencing

Precise Detection of Gene Mutations in Fine-Needle Aspiration Specimens of the Papillary Thyroid Microcarcinoma Using Next-Generation Sequencing

Purpose. To assess the feasibility of next-generation sequencing (NGS) to detect mutations in BRAF, RAS, TERT promoter, and TP53 genes in ultrasound-guided fine-needle aspiration (FNA) biopsy samples of the papillary thyroid microcarcinoma (PTMC). Methods. A total of 135 FNA samples out of 135 patie...

Full description

Saved in:

Bibliographic Details
Main Authors:	Feng-xia Yu, Min-xia Hu, Han-xue Zhao, Li-juan Niu, Xue-yu Rong, Wei-hua Li, Qiang Zhu, Jian-ming Ying, Ning Lyu
Format:	Article
Language:	English
Published:	Wiley 2019-01-01
Series:	International Journal of Endocrinology
Online Access:	http://dx.doi.org/10.1155/2019/4723958
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Clinical Treatment Status of Papillary Thyroid Microcarcinoma
by: Liu Tong, Meng Kexin, Zhu Ying, Fan Fengjing, Wang Bei
Published: (2025-03-01)

Thyroid Papillary Microcarcinoma - Carcinoma with Clinically Benign Behaviour
by: Hitesh R Singhavi, et al.
Published: (2023-12-01)

Therapeutic Outcomes of Patients with Multifocal Papillary Thyroid Microcarcinomas and Larger Tumors
by: Soh-Ching Ng, et al.
Published: (2017-01-01)

The role of repeat fine needle aspiration in managing indeterminate thyroid nodules
by: Laura Allen, et al.
Published: (2019-03-01)

Whether Detection of Gene Mutations Could Identify Low- or High-Risk Papillary Thyroid Microcarcinoma? Data from 393 Cases Using the Next-Generation Sequencing
by: Lei Jin, et al.
Published: (2024-01-01)

Battle of the axes: simulation-based assessment of fine needle aspiration biopsies for thyroid nodules
by: Shireen Samargandy, et al.
Published: (2022-08-01)

Fine-Needle Aspiration Cytology of Parathyroid Carcinoma Mimic Hürthle Cell Thyroid Neoplasm
by: Chutintorn Sriphrapradang, et al.
Published: (2014-01-01)

Detection of BRAF V600E in Fine-Needle Aspiration Samples of Thyroid Nodules by Droplet Digital PCR
by: Sang-Yu Lu, et al.
Published: (2022-01-01)

A Papillary Thyroid Microcarcinoma Revealed by a Single Bone Lesion with No Poor Prognostic Factors
by: Yann Godbert, et al.
Published: (2013-01-01)

Metastatic Renal Cell Cancer to Thyroid Diagnosed by Endoscopic Ultrasound Guided Fine Needle Aspiration Technique
by: Yousef Abdel-Aziz, et al.
Published: (2017-01-01)

Cytomorphological traits of fine-needle aspirates of hyalinizing trabecular tumor of the thyroid gland: A brief report
by: Fei Wang, et al.
Published: (2023-07-01)

Analysis of the service needs of outpatients undergoing thyroid fine needle aspiration biopsy based on the Kano model
by: Xiaoqin Wang, et al.
Published: (2025-01-01)

THE USE OF ARTIFICIAL INTELLIGENCE IN THE THERAPEUTIC MANAGEMENT OF PAPILLARY THYROID MICROCARCINOMA: A RANDOMIZED CONTROLLED TRIAL PROTOCOL
by: Ramona Elena Teiu, et al.
Published: (2024-12-01)

Metastatic Chordoma: A Diagnostic Challenge on Fine Needle Aspiration
by: Ghassan Tranesh, et al.
Published: (2016-01-01)

A Rare Complication of Fine-Needle Aspiration of Neck Structures
by: Yazeed M. Qadadha, et al.
Published: (2021-01-01)

Telediagnosis of Transbronchial Fine Needle Aspirations – A Feasibility Study
by: K. Kayser, et al.
Published: (2000-01-01)

Risk Factors for Cervical Lymph Node Metastasis of Papillary Thyroid Microcarcinoma: A Single-Center Retrospective Study
by: Feng Cheng, et al.
Published: (2019-01-01)

Malignancy Risk and Related Factors of Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance in Thyroid Fine Needle Aspiration
by: So-hyeon Hong, et al.
Published: (2018-01-01)

A Case of Adenomatous Goiter Involving Diffuse, Acute, and Painful Thyroid Enlargement after Fine-Needle Aspiration Cytology
by: Toshiro Shimo, et al.
Published: (2014-01-01)

EU-TIRADS-Based Omission of Fine-Needle Aspiration and Cytology from Thyroid Nodules Overlooks a Substantial Number of Follicular Thyroid Cancers
by: Tamas Solymosi, et al.
Published: (2021-01-01)

Dependence of DNA-Histograms on The Sampling Techniques in Fine Needle Aspirates of the Breast
by: A. Elzagheid, et al.
Published: (2002-01-01)

Carbimazole-induced atypia – A mimicker of malignancy in fine-needle aspiration cytology
by: M. Aswin Manikandan, et al.
Published: (2023-07-01)

Nuclear DNA Content of Fine Needle Aspirates of Invasive Ductal Carcinomas of the Breast
by: Sudip Sarker, et al.
Published: (1997-01-01)

Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy Device for Lymphadenopathy
by: Yuki Tanisaka, et al.
Published: (2021-01-01)

Role of fine-needle aspiration cytology in the diagnosis of erosive polyarticular tophaceous gout
by: Sonu Kalyan, et al.
Published: (2020-01-01)

Active surveillance for adult low-risk papillary thyroid microcarcinoma—a review focused on the 30-year experience of Kuma Hospital—
by: Yasuhiro Ito, et al.
Published: (2024-01-01)

The added value of shear wave elastography when combined to conventional ultrasonography and fine-needle aspiration cytology in detection of malignant thyroid nodule
by: Ahmed Adel Abdallah, et al.
Published: (2024-08-01)

CXCR3, CCR5, and CRTH2 Chemokine Receptor Expression in Lymphocytes Infiltrating Thyroid Nodules with Coincident Hashimoto’s Thyroiditis Obtained by Fine Needle Aspiration Biopsy
by: Jan Jiskra, et al.
Published: (2016-01-01)

Scalp Melanoma Diagnosed by Fine Needle Aspiration Cytology in a Tertiary Health Center
by: A. B. Zarami, et al.
Published: (2015-01-01)

Fine-Needle Aspiration Cytology of Ewing’s Sarcoma of Thoracic Spine with Extension into the Intradural Space
by: Sandhya Bordia, et al.
Published: (2014-01-01)

The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic Cancer
by: Mark Nicaud, et al.
Published: (2010-01-01)

Cysticercosis: Hooked by a Hooklet on Fine Needle Aspiration Cytology—A Case Report
by: Manav Sawhney, et al.
Published: (2013-01-01)

Analysis of Ploidy in Hypopharyngeal Cancer by Laser Scanning Cytometry on Fine Needle Aspirate Biopsies
by: Andreas O.H. Gerstner, et al.
Published: (2003-01-01)

Correction: The added value of shear wave elastography when combined to conventional ultrasonography and fine-needle aspiration cytology in detection of malignant thyroid nodule
by: Ahmed Adel Abdallah, et al.
Published: (2025-01-01)

Comparison of Ultrasound-Guided Fine-Needle Cytology Quality in Thyroid Nodules with 22-, 23-, and 25-Gauge Needles
by: YiJie Dong, et al.
Published: (2021-01-01)

Anaplastic (undifferentiated) carcinoma of pancreas, an uncommon variant: Diagnosed on endoscopic-guided fine needle aspiration
by: Md Ali Osama, et al.
Published: (2023-07-01)

Immediate Surgery Might Be a Better Option for Subcapsular Thyroid Microcarcinomas
by: Jun Jiang, et al.
Published: (2019-01-01)

The Utility of Endoscopic Ultrasound Guided Fine Needle Aspiration in the Diagnosis of Infectious Diseases—Report of Three Cases
by: Mauro Ajaj Saieg, et al.
Published: (2013-01-01)

Does Onsite Cytotechnology Evaluation Improve the Accuracy of Endoscopic Ultrasound-Guided Fine-Needle Aspiration Biopsy?
by: Fahad Alsohaibani, et al.
Published: (2009-01-01)

Fine-Needle Aspiration Biopsy and Endoscopic Ultrasound for Pretreatment Pathological Diagnosis of Gastric Gastrointestinal Stromal Tumors
by: Hiroaki Ito, et al.
Published: (2012-01-01)