Identification of candidate nsSNPs of the human FNDC5 gene and their structural and functional consequences using in silico analysis

Abstract Fibronectin type-III domain containing protein-5 (FNDC5), predominantly expressed in skeletal muscles, encodes FNDC5 transmembrane-protein. A segment of this protein is cleaved and secreted into blood as irisin, which promotes browning of white adipose tissue, leading to energy expenditure....

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Bibliographic Details
Main Authors: Sadaf Majeed, Hira Moin, Maaz Waseem, Zoya Khalid, Sumra Wajid Abbasi, Kashaf Rasool
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-83254-1
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