The immunopeptidome of colon cancer cells treated with topoisomerase inhibiting drug reveals differential as well as common endogenous protein sampling and display of MHC I-associated peptides

Immunotherapy options for microsatellite stable (MSS) colorectal cancer are currently very limited. The lack of detectably unique or altered immunogens in the tumor microenvironment may be a factor. Radiation and chemotherapy may enhance immunotherapy by increasing cancer cell visibility through Maj...

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Bibliographic Details
Main Authors: Deepa Bedi, Mohammed Hassan, Alehegne Yirsaw, Biba Vikas, Pran Datta, Temesgen Samuel
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Molecular & Cellular Oncology
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Online Access:https://www.tandfonline.com/doi/10.1080/23723556.2025.2471640
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