3-Arylcoumarin inhibits vascular calcification by inhibiting the generation of AGEs and anti-oxidative stress

3-Arylcoumarin inhibits vascular calcification by inhibiting the generation of AGEs and anti-oxidative stress

Objective This work aims to screen drugs for preventing and treating vascular calcification. Method: We screened a series of 3-arylcoumarins for the detection of vascular calcification-associated factors using human aortic vascular smooth muscle cells.Results We found that compounds 14 and 32 signif...

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Bibliographic Details
Main Authors: YuFei Li, Yinbo Pan, Liying Wang, Xiaojing Wang, Haiping Chu, Yan Li, Jie Sun, Yanling Mu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
3-arylcoumarin derivatives
vascular calcification
AGEs
oxidative stress
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2022.2109024
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https://www.tandfonline.com/doi/10.1080/14756366.2022.2109024

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