Study protocol of a German multi-center, observer-blind, randomized, and actively controlled parallel-group trial comparing maintenance electroconvulsive therapy to treatment as usual for relapse prevention in clozapine resistant schizophrenia

Study protocol of a German multi-center, observer-blind, randomized, and actively controlled parallel-group trial comparing maintenance electroconvulsive therapy to treatment as usual for relapse prevention in clozapine resistant schizophrenia

Abstract Background Schizophrenia is one of the most severe and costly mental disorders in terms of human suffering and societal expenditure. About 15–30% of patients do not respond to all known antipsychotics, including clozapine, the current gold standard in these cases. Electroconvulsive therapy...

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Bibliographic Details
Main Authors: Anton Deicher, Sebastian Karl, Marie-Luise Otte, Johannes Knabbe, Bernadette Wendel, Maria Gose, R. Christian Wolf, Alexander Sartorius
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Psychiatry
Subjects:
Electroconvulsive therapy
ECT
Maintenance electroconvulsive therapy
mECT
Clozapine-resistant schizophrenia
CRS
Online Access:https://doi.org/10.1186/s12888-025-06990-2
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https://doi.org/10.1186/s12888-025-06990-2

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