Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes
Summary: Alveolar macrophages (AMs) are lung-resident macrophages critical to lung homeostasis and immunity. Replacement of embryonic-derived tissue-resident AMs (TRAMs) by circulating monocyte-derived AMs (MoAMs) reshapes the functionality of AMs and host susceptibility to respiratory diseases. How...
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| Main Authors: | Jinjing Zhang, Tao Wang, Yanling Wang, Ying Li, Lu Wang, Jiepu Wang, Yuxuan Miao, Feng Xu, Yushi Yao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | Cell Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725003420 |
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