Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes

Summary: Alveolar macrophages (AMs) are lung-resident macrophages critical to lung homeostasis and immunity. Replacement of embryonic-derived tissue-resident AMs (TRAMs) by circulating monocyte-derived AMs (MoAMs) reshapes the functionality of AMs and host susceptibility to respiratory diseases. How...

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Bibliographic Details
Main Authors: Jinjing Zhang, Tao Wang, Yanling Wang, Ying Li, Lu Wang, Jiepu Wang, Yuxuan Miao, Feng Xu, Yushi Yao
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725003420
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