Effects of Clozapine, Haloperidol, and the NMDA Antagonist Ketamine on Novel Object Recognition in <i>Gnathonemus petersii</i>: A New Possible Model for Schizophrenia Research

Effects of Clozapine, Haloperidol, and the NMDA Antagonist Ketamine on Novel Object Recognition in <i>Gnathonemus petersii</i>: A New Possible Model for Schizophrenia Research

In animal models, ketamine, a non-competitive N-methyl-D-aspartate (NMDA) antagonist, induces schizophrenia-like symptoms, such as positive and negative symptoms, as well as cognitive deficits. In the present study, we evaluated the behavioral responses and the number of EODs (electric organ dischar...

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Bibliographic Details
Main Authors: Petra Horká, Josefina Mavrogeni, Veronika Langová, Pavel Horký, Jan Hubený, Ivana Chrtková, Karel Valeš, Martin Kuchař, Jiří Horáček
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Fishes
Subjects:
cognition
antipsychotics
novel object recognition
NORT
behavior
ketamine
Online Access:https://www.mdpi.com/2410-3888/10/5/229
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