APOE Genotype and Statin Response: Evidence From the UK Biobank and All of Us Program

APOE Genotype and Statin Response: Evidence From the UK Biobank and All of Us Program

ABSTRACT APOE genotype may affect statin response. Using UK Biobank (UKB) and All of Us (AoU) data, we aimed to investigate associations between APOE genotype, statin use, and key health outcomes. Our analysis included UKB baseline data and linked mortality records (389,843–452,189 participants), an...

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Main Authors: Innocent G. Asiimwe, Andrea L. Jorgensen, Munir Pirmohamed, the Multimorbidity Mechanism and Therapeutic Research Collaborative (MMTRC)
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Clinical and Translational Science
Subjects:
All of Us Research Program
APOE genotype
lipid response
major adverse cardiovascular events
mortality
statins
Online Access:https://doi.org/10.1111/cts.70314
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https://doi.org/10.1111/cts.70314

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