Two natural products from the seeds of Citrus reticulata Blanco (Rutaceae) inhibit estrogen biosynthesis by regulating the PI3K-aromatase pathway

IntroductionThe seeds of Citrus reticulata Blanco (Rutaceae) (SCR), a traditional Chinese medicine derived from Citrus, is known for its diverse bioactivities, including potential anti-breast cancer effects, but the mechanism of action remains unclear.MethodsThis study aims to elucidate the active i...

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Bibliographic Details
Main Authors: Xing Yang, Xi Chen, Chunqiao Shi, Qian Zhang, Qian Liu, Chunyan Zhou, Fawu Dong, Jinsong Su, Deming Liu, Yi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1583409/full
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