Sacubitril Does Not Exert Proarrhythmic Effects in Combination with Different Antiarrhythmic Drugs

Sacubitril Does Not Exert Proarrhythmic Effects in Combination with Different Antiarrhythmic Drugs

<b>Background:</b> Previous studies suggest a direct effect of sacubitril on cardiac electrophysiology and indicate potential arrhythmic interactions between sacubitril and antiarrhythmic drugs. Therefore, the aim of this study was to explore the electrophysiologic effects of combining s...

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Bibliographic Details
Main Authors: Christian Ellermann, Carlo Mengel, Julian Wolfes, Felix K. Wegner, Benjamin Rath, Julia Köbe, Lars Eckardt, Gerrit Frommeyer
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
drug-induced proarrhythmia
Langendorff
arrhythmia
torsade de pointes
safety electrophysiology
ventricular tachycardia
Online Access:https://www.mdpi.com/1424-8247/18/2/230
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https://www.mdpi.com/1424-8247/18/2/230

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