Antimicrobial susceptibility and resistance mechanisms to antipseudomonal β-lactams in Pseudomonas aeruginosa isolates from blood

Antimicrobial susceptibility and resistance mechanisms to antipseudomonal β-lactams in Pseudomonas aeruginosa isolates from blood

ABSTRACT Bloodstream infection caused by Pseudomonas aeruginosa with antimicrobial resistance can be difficult to treat. Herein, we investigated antimicrobial susceptibility to major antipseudomonal β-lactams and analyzed the relationship between resistance mechanisms and susceptibilities in P. aeru...

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Main Authors: Mika Murata, Kosuke Kosai, Fujiko Mitsumoto-Kaseida, Norihito Kaku, Hiroo Hasegawa, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:Microbiology Spectrum
Subjects:
bloodstream infection
resistance to antipseudomonal β-lactams
gene expression
ceftolozane/tazobactam
cefiderocol
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02790-24
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https://journals.asm.org/doi/10.1128/spectrum.02790-24

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