Sorafenib-treated hepatocellular carcinoma with or without prior direct-acting antiviral therapy for hepatitis C: outcomes and survival

Sorafenib-treated hepatocellular carcinoma with or without prior direct-acting antiviral therapy for hepatitis C: outcomes and survival

Abstract Background Hepatitis C virus (HCV) has been linked to lower tumor growth rates, higher sorafenib efficacy, and greater survival of patients treated for hepatocellular carcinoma (HCC). In real-world settings, we tried to elucidate the effectiveness of sorafenib therapy for patients with HCV-...

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Main Authors: Rania Lithy, Mohamed Kohla, Hossam Dabees, Hend Ibrahim Shousha, Ehab Fawzy, Eman M. F. Barakat, Mohamed El-Kassas, Mona Shoukry Aziz, Eman Elkhateeb, Ashraf Omar Abdelaziz, Mohamed Omar Abdelmalek, Ali Azmy, Ahmed Tawheed, Reem Abdelghafour, Hossam Taha, Mohamed Mahmoud Nabeel, Mohamed A. Medhat, Dalia Ghoraba, Hamdy Sayed, Anwar Nassief, Mostafa Elhelbawy, Tamer Elbaz, Ahmed Radwan, Safaa Ragab Askar, Eman Marwan, Eman Rewisha, Ahmed Hosni Abdelmaksoud, Sayed Hassan Ahmed, Nevien Fouad Elfouly, Nermeen Abdeen, Ahmed Ramadan, Asmaa A. Abdeltawab, Mostafa Abd Alfattah Shamkh, Yasser Arafat Abdelrazek, Ammar Alrajhi, Sayed Ahmed Sayed, Ahmed A. Sleem, Rasha Salah Hussein, Allam Elsayed Allam, Omnia A. Seyam, Mohamed Said, representing The Egyptian Network for the Study of H. C. C. (ENSH) group
Format: Article
Language:English
Published: SpringerOpen 2025-08-01
Series:Egyptian Liver Journal
Subjects:
Hepatocellular carcinoma
Hepatitis C virus
Direct-acting antivirals
Adverse events
Survival
Online Access:https://doi.org/10.1186/s43066-025-00448-6
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https://doi.org/10.1186/s43066-025-00448-6

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