Enhancement of retinal Müller glia’s phagocytic activity against hard exudates by conbercept via activation of PPARγ-CD36 axis in diabetic retinopathy

Enhancement of retinal Müller glia’s phagocytic activity against hard exudates by conbercept via activation of PPARγ-CD36 axis in diabetic retinopathy

AIM: To investigate the effects and the underlying mechanism(s) of conbercept on the phagocytosis of hard exudates (HEs) by Müller glia in diabetic retinopathy (DR). METHODS: Twenty-one eyes from 17 patients with diabetic macular edema (DME) underwent optical coherence tomography (OCT) imaging to ex...

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Bibliographic Details
Main Authors: Ying-Ying Zhu, Shi-Yue Qin, Hai Xie, Yin-Ping Liu, Xiao-Sa Li, Chao-Yang Zhang, Yan-Chun Zhang, Jing-Fa Zhang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2025-07-01
Series:International Journal of Ophthalmology
Subjects:
conbercept
müller glia
oxidized low-density lipoprotein
phagocytosis
vascular endothelial growth factor
Online Access:http://ies.ijo.cn/en_publish/2025/7/20250707.pdf
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http://ies.ijo.cn/en_publish/2025/7/20250707.pdf

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