Time‐Lapse Acquisition of Both Freely Secreted Proteome and Exosome Encapsulated Proteome in Live Organoids’ Microenvironment

Time‐Lapse Acquisition of Both Freely Secreted Proteome and Exosome Encapsulated Proteome in Live Organoids’ Microenvironment

Abstract Proteomic communications in neighboring microenvironments during early organ development is a dynamic process that continuously reshapes human embryonic stem cells (hESCs) developmental fate. Such dynamic proteomic alteration in the microenvironment consists of both freely secreted proteome...

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Bibliographic Details
Main Authors: Haoni Yan, Aynur Abdulla, Aiting Wang, Shuyu Ding, Manlin Zhang, Yizhi Zhang, Tsz Yui Zhuang, Leqi Wu, Yan Wang, Rongrong Ren, Lai Jiang, Xianting Ding
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
cerebral organoids
exosomes
microenvironment
microfluidic platform
proteomics
Online Access:https://doi.org/10.1002/advs.202406509
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